tr.v. es·tranged, es·trang·ing, es·trang·es
1. To make hostile, unsympathetic, or indifferent; alienate.
2. To remove from an accustomed place or set of associations.
[Middle English estraungen, from Old French estrangier, from Latin extrnere, to treat as a stranger, disown, from extrneus, foreign; see strange.]
es·trangement n.
es·tranger n.
Synonyms: estrange, alienate, disaffect
These verbs refer to disruption of a bond of love, friendship, or loyalty. Estrange and alienate are often used with reference to two persons whose harmonious relationship has been replaced by hostility or indifference: Political disagreements led to quarrels that finally estranged the two friends. His persistent antagonism alienated his wife.
Disaffect usually implies discontent, ill will, and disloyalty within the membership of a group: Colonists were disaffected by the royal governor's actions.
These verbs refer to disruption of a bond of love, friendship, or loyalty. Estrange and alienate are often used with reference to two persons whose harmonious relationship has been replaced by hostility or indifference: Political disagreements led to quarrels that finally estranged the two friends. His persistent antagonism alienated his wife.
Disaffect usually implies discontent, ill will, and disloyalty within the membership of a group: Colonists were disaffected by the royal governor's actions.
More:
http://www.thefreedictionary.com/estrangement